Broad chromosomal domains of histone modification patterns in C. elegans
نویسندگان
چکیده
منابع مشابه
Broad chromosomal domains of histone modification patterns in C. elegans.
Chromatin immunoprecipitation identifies specific interactions between genomic DNA and proteins, advancing our understanding of gene-level and chromosome-level regulation. Based on chromatin immunoprecipitation experiments using validated antibodies, we define the genome-wide distributions of 19 histone modifications, one histone variant, and eight chromatin-associated proteins in Caenorhabditi...
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Recent advances demonstrate that epigenome changes can also cause phenotypic diversity and can be heritable across generations, indicating that they may play an important role in evolutionary processes. In this study, we analyzed the chromosomal distribution of several histone modifications in five elite maize cultivars (B73, Mo17, Chang7-2, Zheng58, ZD958) and their two wild relatives (Zea may...
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Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification.
Transcription by RNA polymerase II (RNAPII) is accompanied by a conserved pattern of histone modifications that plays important roles in regulating gene expression. The establishment of this pattern requires phosphorylation of both Rpb1 (the largest RNAPII subunit) and the elongation factor Spt5 on their respective C-terminal domains (CTDs). Here we interrogated the roles of individual Rpb1 and...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2010
ISSN: 1088-9051
DOI: 10.1101/gr.115519.110